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  1. Multiple sclerosis in south Cambridgeshire : incidence and prevalence based on a district register.

    Article - En anglais

    Study objective

    To establish an updated prevalence and incidence figure for multiple sclerosis on 1 July 1993, to determine the fate of the 374 patients prevalent in 1990, and to establish the origin of incident patients.


    Case ascertainment was from several sources including departmental records, local branches of the Multiple Sclerosis Society, general practitioners, nursing homes, and residential facilities for the disabled.

    Data collection was by personal interview using a standardised questionnaire and by retrospective analysis of departmental case notes.

    A prospective incidence register of newly diagnosed patents was maintained from 1990.


    The Cambridge Health District of East Anglia covering 340 910 hectares in area and a population of 290 700.


    Altogether 441 patients prevalent on 1 July 1993 were identified, of whom 328 were contacted so that clinical data could be collected.

    Seventy patients (16%) either declined to take part or access was denied by their general practitioner ; 8 (2%) had died ; and 35 (8%) were too ill or failed to respond to several requests for contact.

    Main results

    A comprehensive re-evaluation of the south Cambridgeshire multiple sclerosis register revealed a prevalence of 4411290 700 population (152/10 5) for all disease classifications on 1 July 1993.

    This represented an increase of 18% from 1990 and was a result of 138 additions and 71 deletions from the original list of 374 patients. (...)

    Mots-clés Pascal : Sclérose en plaque, Epidémiologie, Prévalence, Incidence, Homme, Registre, Royaume Uni, Europe, Système nerveux pathologie, Système nerveux central pathologie, Maladie inflammatoire

    Mots-clés Pascal anglais : Multiple sclerosis, Epidemiology, Prevalence, Incidence, Human, Register, United Kingdom, Europe, Nervous system diseases, Central nervous system disease, Inflammatory disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0317965

    Code Inist : 002B17F. Création : 10/04/1997.