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  1. Validation of questionnaire and bronchial hyperresponsiveness against respiratory physician assessment in the diagnosis of asthma.

    Article - En anglais


    The Tasmanian Asthma Survey (TAS) and the International Study of Asthma and Allergies in Childhood (ISAAC) have used questionnaires to measure the prevalence of asthma in adults and children.

    We have investigated the validity of these questionnaires by comparing response to questionnaire with a physician assessment of asthma status in the past 12 months.


    Ninety-three adults were given the TAS questionnaire to complete and 361 children were given the ISAAC questionnaire.

    Ninety-one adults and 168 children completed bronchial challenge with hypertonic saline.

    A consultation with a respiratory physician blinded to the results of the questionnaire and bronchial challenge was given to all subjects.


    In both adults and children, questionnaires showed high agreement with respiratory physician diagnosis with respect to asthma symptoms in the past 12 months.

    For the TAS questionnaire the positive and negative predictive values (95% confidence limits) for physician diagnosis for adults were 0.89 (0.68-0.98) and 0.94 (0.86-0.98) respectively.

    The instrument was also sensitive 0.80 (0.58-0.93) and highly specific 0.97 (0.90-0.99).

    For the ISAAC questionnaire the positive and negative predictive values for physician diagnosis of asthma in children were 0.61 (0.50-0.71) and 0.94 (0.88-0.98) respectively.

    Sensitivity and specificity were 0.85 (0.73-0.93) and 0.81 (0.76-0.86) respectively. (...)

    Mots-clés Pascal : Asthme, Diagnostic, Etude comparative, Questionnaire, Psychométrie, Validation test, Méthode étude, Autoévaluation, Epidémiologie, Hyperréactivité, Bronche, Poumon, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Allergie, Immunopathologie, Australie, Océanie, Homme

    Mots-clés Pascal anglais : Asthma, Diagnosis, Comparative study, Questionnaire, Psychometrics, Test validation, Investigation method, Self evaluation, Epidemiology, Hyperreactivity, Bronchus, Lung, Respiratory disease, Obstructive pulmonary disease, Allergy, Immunopathology, Australia, Oceania, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0317934

    Code Inist : 002B11B. Création : 10/04/1997.