To determine patients'knowledge of the safe use and toxicity of methotrexate (MTX) and to define educational interventions implemented by a rheumatology nurse that improved patients'understanding of MTX therapy.
One hundred eighty-three patients from a university-based rheumatology clinic who were taking MTX completed an initial knowledge questionnaire concerning the proper use and possible toxicity of MTX.
Following completion, a nurse reviewed the correct answers with each patient and provided written information on MTX.
One hundred thirty-eight of these patients completed a followup questionnaire at the next visit or by mail.
The questionnaires were analyzed, and a total MTX knowledge score was calculated.
MTX knowledge improved significantly between questionnaires ; mean total score (±SD) increased from 7.32 ± 3.99 to 10.23 ± 3.29 (P<0.001).
After accounting for a person's initial questionnaire score, the addition of a supplemental « MTX pocket-card » was associated with a higher score on the followup questionnaire (adjusted odds ratio [OR]=2.37 ; 95% confidence interval [CI] 1.14,4.95 ; P=0.021).
Patients over age 55 were 4 times more likely to have a poorer score compared with patients under age 45 (adjusted OR=0.23 ; 95% CI 0.07,0.73 ; P=0.013).
Knowledge of the toxicity and safe use of MTX was significantly improved by a patient education program utilizing a rheumatology nurse. (...)
Mots-clés Pascal : Arthrite, Homme, Traitement, Chimiothérapie, Toxicité, Méthotrexate, Antirhumatismal, Programme éducatif, Connaissance, Malade, Evaluation, Prévention, Rhumatisme inflammatoire, Questionnaire, Système ostéoarticulaire pathologie
Mots-clés Pascal anglais : Arthritis, Human, Treatment, Chemotherapy, Toxicity, Antirheumatic agent, Educational schedule, Knowledge, Patient, Evaluation, Prevention, Inflammatory joint disease, Questionnaire, Diseases of the osteoarticular system
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0316761
Code Inist : 002B26H. Création : 10/04/1997.