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  1. Methotrexate patient education : A quality improvement study.

    Article - En anglais


    To determine patients'knowledge of the safe use and toxicity of methotrexate (MTX) and to define educational interventions implemented by a rheumatology nurse that improved patients'understanding of MTX therapy.


    One hundred eighty-three patients from a university-based rheumatology clinic who were taking MTX completed an initial knowledge questionnaire concerning the proper use and possible toxicity of MTX.

    Following completion, a nurse reviewed the correct answers with each patient and provided written information on MTX.

    One hundred thirty-eight of these patients completed a followup questionnaire at the next visit or by mail.

    The questionnaires were analyzed, and a total MTX knowledge score was calculated.


    MTX knowledge improved significantly between questionnaires ; mean total score (±SD) increased from 7.32 ± 3.99 to 10.23 ± 3.29 (P<0.001).

    After accounting for a person's initial questionnaire score, the addition of a supplemental « MTX pocket-card » was associated with a higher score on the followup questionnaire (adjusted odds ratio [OR]=2.37 ; 95% confidence interval [CI] 1.14,4.95 ; P=0.021).

    Patients over age 55 were 4 times more likely to have a poorer score compared with patients under age 45 (adjusted OR=0.23 ; 95% CI 0.07,0.73 ; P=0.013).


    Knowledge of the toxicity and safe use of MTX was significantly improved by a patient education program utilizing a rheumatology nurse. (...)

    Mots-clés Pascal : Arthrite, Homme, Traitement, Chimiothérapie, Toxicité, Méthotrexate, Antirhumatismal, Programme éducatif, Connaissance, Malade, Evaluation, Prévention, Rhumatisme inflammatoire, Questionnaire, Système ostéoarticulaire pathologie

    Mots-clés Pascal anglais : Arthritis, Human, Treatment, Chemotherapy, Toxicity, Antirheumatic agent, Educational schedule, Knowledge, Patient, Evaluation, Prevention, Inflammatory joint disease, Questionnaire, Diseases of the osteoarticular system

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0316761

    Code Inist : 002B26H. Création : 10/04/1997.