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  1. Definition and epidemiology of treatment-resistant depression.

    Fascicule - En anglais

    Although many depressed patients do improve with adequate antidepressant treatment, a significant proportion fails to reach acceptable levels of functioning and well-being.

    Currently, however, there is no universally accepted definition of treatment resistance in unipolar depression (TRD).

    This article proposes an operational definition of TRD and discusses partial response, nonresponse, and methodologic issues that emerge in the assessment of resistance.

    Finally, possible predictors of failure to respond are reviewed, and an attempt is made to estimate the prevalence of TRD.

    Mots-clés Pascal : Définition, Epidémiologie, Etat dépressif, Trouble humeur, Résistance, Traitement, Chimiothérapie, Psychotrope, Antidépresseur, Prévalence, Méthode mesure, Article synthèse, Homme

    Mots-clés Pascal anglais : Definition, Epidemiology, Depression, Mood disorder, Resistance, Treatment, Chemotherapy, Psychotropic, Antidepressant agent, Prevalence, Measurement method, Review, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0316380

    Code Inist : 002B18C07A. Création : 10/04/1997.