High socioeconomic status and migration to a higher risk area have been linked to increased breast cancer risk.
To evaluate the occurrence of breast cancer in women of different social class and residential history, we conducted a multicentre case-control study in Italy.
A total of 2569 cases of incident breast cancer were ascertained in northern, central and southern Italy.
The controls were 2588 women admitted for a wide spectrum of acute conditions to the same hospitals where cases had been hospitalized.
The effect of socioeconomic variables was evaluated with multiple logistic regression after stratification and adjustment for age, origin, centre, and selected reproductive and dietary factors.
Compared to housewives, managers and professionals had a 1.7-fold increased risk, whereas the relative risk was 0.7 and 0.6 respectively in helpers and manual workers.
The risk of breast cancer also increased with increasing social level of the husband's occupation and subject's number of years of schooling.
Women who originated in central and southern Italy, and migrated to northern Italy after age 24, but not those who migrated at a younger age, had a relative risk of 0.6 and 0.7 respectively, compared to lifelong residents in northern Italy.
Our findings show that correlates of sociocultural level and place of origin exert an influence on breast cancer risk which is not accounted for completely by known risk factors (i.e. (...)
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Epidémiologie, Statut socioéconomique, Classe sociale, Migration population, Variation géographique, Catégorie socioprofessionnelle, Niveau étude, Italie, Europe, Femme, Homme, Glande mammaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Epidemiology, Socioeconomic status, Social class, Population migration, Geographical variation, Socioeconomic category, Education level, Italy, Europe, Woman, Human, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0315806
Code Inist : 002B20E02. Création : 10/04/1997.