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  1. Determination of PCB metabolites in Canadian human milk.

    Article - En anglais

    Chlorinated biphenyl methylsulfones and biphenylols were determined in samples of human milk from Canadian donors.

    Fifty samples containing an average of 10.8 ng g-1 (w/w) of total PCBs were found to contain an average of 68 pg g-1 of chlorinated biphenyl methylsulfone.

    The major congeners were 3-methylsulfonyl-2,2'4'5,5'-pentachlorobiphenyl, 4-methylsulfonyl-2,2'3'4'5, - pentachlorobiphenyl and 4-methylsulfonyl-2,2'3'5,5'6'-hexachlorobiphenyl.

    Twelve of these samples were analyzed for five chlorinated biphenylols and the 4-methoxy-2,2'3,4'5,5'6-heptachlorobiphenylol congener was detected in all at an average concentration of 1.9 pg g-1.

    The chlorinated biphenylols appear to be minor residual metabolites in human milk from the general population.

    The fifty samples with an average of 8.4 ng g-1 of p, p'-DDE also contained an average of 16.5 pg g-1 of the corresponding methylsulfone.

    Both the total PCB methylsulfone and p, p'DDE methylsulfone were correlated with total PCB and p, p'DDE contents, respectively.

    Mots-clés Pascal : Biphényle(polychloro), Polluant, Environnement, Canada, Amérique du Nord, Amérique, Homme, Taux, Analyse quantitative, Lait femme, Métabolite, Epidémiologie, Liquide biologique

    Mots-clés Pascal anglais : Polychlorobiphenyl, Pollutant, Environment, Canada, North America, America, Human, Rate, Quantitative analysis, Human milk, Metabolite, Epidemiology, Biological fluid

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0314243

    Code Inist : 002B03M01. Création : 10/04/1997.