The rapidly expanding mariculture and commercial region along the southern coast of China has experienced sporadic outbreaks of paralytic shellfish poisoning for nearly 30 years, yet virtually nothing is known of the nature of that toxicity or of the causative organisms.
This study presents the first direct comparisons of the high performance liquid chromatography toxin composition profiles of shellfish implicated in paralytic shellfish poisoning outbreaks in Daya Bay with Alexandrium tamarense cultures established from those waters.
The three cultures that were analyzed produced an unusually high proportion of the low potency N-sulfocarbamoyl toxins Cl and C2 (nearly 90% of the total), and only trace quantities of the other saxitoxin derivatives.
Total toxicity was thus very low with mild acid extraction, ranging between 7.2 and 12.7 fmole cell-1, or 0.7-0.9 pg saxitoxin equiv. cell-1.
Following acid hydrolysis using the standard AOAC extraction method, the dominant toxins in the cultures were gonyautoxins 2 and 3 and decarbamoyl gonyautoxins 2 and 3. Total potency increased fourfold to 2.6-3.4 pg saxitoxin equiv. cell-1 following acid hydrolysis.
These cultures are thus at the low end of the range of toxicities recorded for members of the A. tamarense species complex.
Two scallop samples and one mussel sample collected from Daya Bay during paralytic shellfish poisoning episodes in 1990 and 1991 were also analyzed following the AOAC extraction procedure. (...)
Mots-clés Pascal : Intoxication paralysante par mollusque, Chine, Asie, Epidémiologie, Homme, Toxine, Mollusque comestible, Crustacé comestible, Contamination, Toxicité, Pyrrophycophyta, Algae, Thallophyta, Origine végétale, Intoxication alimentaire, Isolement, Saxitoxine, Alexandrium tamarense
Mots-clés Pascal anglais : Paralytic shellfish poisoning, China, Asia, Epidemiology, Human, Toxin, Edible mollusc, Edible crustacean, Contamination, Toxicity, Pyrrophycophyta, Algae, Thallophyta, Plant origin, Food poisoning, Isolation
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0313986
Code Inist : 002B03H. Création : 10/04/1997.