On the basis of embryology and clinical experience, we have defined here an anterior commissure (AC) subsite of the human larynx and have addressed the issue as to whether the degree of involvement of this subsite is related to the outcome of glottic cancer, in terms of local control within 5 years of therapy.
Retrospective analysis of 534 patients included 1) classification of patients according to the TNM, 2) actuarial evaluation of the outcome, 3) reclassification of patients according to the involvement of the AC subsite, and 4) reevaluation of the outcome according to this latter classification.
The results showed that the outcome was not well correlated with TNM classification, whereas patients with progressively heavier involvement of the AC subsite had a progressively worse outcome.
On the basis of these data, we suggest that TNM classification of cancer involving the AC be implemented by an AC classification, in order to better forecast the prognosis and design specific conservative surgery.
Mots-clés Pascal : Carcinome, Glotte, Corde vocale, Homme, Classification, Pronostic, Stade clinique, Nosologie, Epidémiologie, Larynx, Voie respiratoire supérieure, Tête cou, Larynx pathologie, ORL pathologie, Tumeur maligne, Commissure antérieure
Mots-clés Pascal anglais : Carcinoma, Glottis, Vocal cord, Human, Classification, Prognosis, Clinical stage, Nosology, Epidemiology, Larynx, Upper respiratory tract, Head and neck, Larynx disease, ENT disease, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0305614
Code Inist : 002B10B01. Création : 10/04/1997.