Objectives-Hair bleaches containing persulphates have been identified as the cause of occupational asthma in hairdressers.
Also employees in persulphate production with occupational asthma have been described.
It was the aim of this study to give an estimate of the prevalence of asthma due to persulphates in chemical workers with exposure to ammonium and sodium persulphate.
Methods-A cross sectional study was performed in 32 of 33 employees of a persulphate producing chemical plant.
Eighteen of 23 workmen from the same plant with no exposure to persulphates were taken as controls.
Also, information was collected from medical records of the seven subjects who had left the persulphate production for medical reasons since 1971.
Data were recalled by a questionnaire, skin prick tests were performed with five environmental allergens, and ammonium and sodium persulphate (80 mg/ml).
Specific immunoglobulin E (IgE) to the same environmental allergens as in the skin test, and total IgE were measured.
Lung function and bronchial responsiveness to histamine were assessed by standard procedures.
Workplace concentrations of ammonium and sodium persulphate were estimated by area and personal monitoring.
The amount of persulphate was analysed as sulphur by inductively coupled plasma emission spectrometry.
Work related rhinitis was reported by one subject with exposure to persulphates, conjunctivitis and bronchitis were reportedly related to work by two controls. ...
Mots-clés Pascal : Allergène, Sulfate Composé organique, Exposition professionnelle, Homme, Industrie chimique, Asthme, Toxicité, Médecine travail, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Allergie, Immunopathologie, Persulfate
Mots-clés Pascal anglais : Allergen, Sulfates Organic compounds, Occupational exposure, Human, Chemical industry, Asthma, Toxicity, Occupational medicine, Respiratory disease, Obstructive pulmonary disease, Allergy, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0295645
Code Inist : 002B06C02. Création : 199608.