Standardized criteria for Crohn's disease (CD) have only recently been developed, and prospective community-based incidence studies have been performed only during the past 3 decades.
Geographic variations in incidence may therefore be due to differences in study design.
From 1 January 1990 to 31 December 1993 all new cases of CD in four counties in southeastern Norway were prospectively registered.
A total of 225 new cases yielded an annual incidence of 5.8/105, with the highest incidence in mixed rural-urban areas.
A peak of 11.2/105 in the annual incidence was found for the age group 15 to 24 years, with no significant differences in the overall annual incidence by gender.
An average duration of 6 months of disease before diagnosis was unchanged during the 4 years.
About half of the patients had isolated colonic disease, and one-quarter had isolated small-bowel disease.
This study confirms the high incidence figures for Scandinavia, with a particularly high incidence in mixed rural-urban areas.
Ileocolonoscopy improves the accuracy of the diagnosis and of the determination of disease extent, which may have therapeutic implications for the treatment and follow-up of patients.
Mots-clés Pascal : Entérite Crohn, Incidence, Prévention, Dépistage, Endoscopie, Colonoscopie, Symptomatologie, Epidémiologie, Homme, Norvège, Europe, Appareil digestif pathologie, Intestin pathologie, Maladie inflammatoire
Mots-clés Pascal anglais : Crohn disease, Incidence, Prevention, Medical screening, Endoscopy, Colonoscopy, Symptomatology, Epidemiology, Human, Norway, Europe, Digestive diseases, Intestinal disease, Inflammatory disease
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0289251
Code Inist : 002B30A01A2. Création : 199608.