logo BDSP

Base documentaire

  1. Intersalt revisited : further analyses of 24 hour sodium excretion and blood pressure within and across populations.

    Article - En anglais

    Objectives-To assess further the relation in Intersalt of 24 hour urinary sodium to blood pressure of individuals and populations, and the difference in blood pressure from young adulthood into middle age.

    Design-Standardised cross sectional study within and across populations.

    Setting-52 population samples in 32 countries

    Subjects-10 074 men and women aged 20-59.

    Main outcome measure-Association of sodium and blood pressure from within population and cross population multiple linear regression analyses with multivariate correction for regression dilution bias.

    Relation of sample median daily urinary sodium excretion to difference in blood pressure with age.


    In within population analyses (n=10 074), individual 24 hour urinary sodium excretion higher by 100 mmol (for example, 170 v 70 mmol) was associated with systolic/diastolic blood pressure higher on average by 310 to 6/3 mm Hg (with and without body mass in analyses).

    Associations were larger at ages 40-59.

    In cross population analyses (n=52), sample median 24 hour sodium excretion higher by 100 mmol was associated with median systolic/diastolic pressure higher on average by 5-7/2-4 mm Hg, and estimated mean difference in systolicldiastolic pressure at age 55 compared with age 25 greater by 10-11/6 mm Hg.

    Conclusions-The strong, positive association of urinary sodium with systolic pressure of individuals concurs with Intersalt cross population findings and results of other studies.

    Higher urina...

    Mots-clés Pascal : Corrélation, Taux concentration, Sodium, Urine, Pression sanguine, Exploration clinique, Evolution, Age, Ethnie, Etude cohorte, Homme, Appareil urinaire, Appareil circulatoire, Etude Intersalt

    Mots-clés Pascal anglais : Correlation, Concentration factor, Sodium, Urine, Blood pressure, Clinical investigation, Evolution, Age, Ethnic group, Cohort study, Human, Urinary system, Circulatory system

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0279778

    Code Inist : 002B12B05B. Création : 199608.