The study assesses the clinical features of individuals that best enable an effective selective screening of the adult population for dyslipidemia.
The results of the population-based 1990 Saskatchewan Heart Health Survey were examined.
Dyslipidemia was defined as a total cholesterol (TC) to high-density lipoprotein cholesterol (HDL) ratio of =5. In total, 805 men and 782 women, 18-74 years of age, had their plasma cholesterol measured.
Using TC screening of the entire population as recommended by the Canadian Consensus Conference on Cholesterol would correctly identify 79% of those with dyslipidemia (sensitivity) and 67% of those with a normal profile (specificity).
However, if one performs lipoprotein analysis on only those with a high waist-to-hip circumference ratio (WHR), 44% of the population would need to be screened to correctly identify 71% of those with dyslipidemia (sensitivity), and 66% of those with a normal profile (specificity).
A high WHR is an especially strong predictor of dyslipidemia in young adults.
In conclusion, a high WHR may provide an effective means of selective screening of the adult population for dyslipidema.
Mots-clés Pascal : Hypercholestérolémie, Homme, Dépistage, Critère sélection, Facteur risque, Cholestérol, Canada, Amérique du Nord, Amérique, Lipide, Métabolisme pathologie, Hyperlipoprotéinémie, Facteur prédictif
Mots-clés Pascal anglais : Hypercholesterolemia, Human, Medical screening, Selection criterion, Risk factor, Cholesterol, Canada, North America, America, Lipids, Metabolic diseases, Hyperlipoproteinemia, Predictive factor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0275815
Code Inist : 002B22A. Création : 199608.