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  1. Effect of ambient solar ultraviolet radiation on incidence of squamous-cell carcinoma of the eye.

    Article - En anglais

    Background We have investigated the geographic distribution of squamous-cell carcinoma of the eye to assess whether solar ultraviolet light is a risk factor for this disease.

    Methods We used routinely collected population-based cancer incidence data and published measurements of ambient solar ultraviolet light in our analysis.

    Findings The incidence of squamous-cell carcinoma of the eye declined by 49% for each 10° increase in latitude (p<0.0001), falling from more than 12 cases per million per year in Uganda (latitude 0.3°) to less than 0.2 per million per year in the UK (latitude>50°). Solar ultraviolet radiation decreases with increasing latitude, and the incidence of squamous-cell carcinoma of the eye decreased by 29% per unit reduction in ultraviolet exposure (p<0.0001).

    Interpretation Our results are compatible with the hypothesis that exposure to solar ultraviolet light is an important cause of squamous-cell carcinoma of the eye.

    Mots-clés Pascal : Carcinome épidermoïde, Conjonctive, Rayonnement UVB, Rayonnement solaire, Epidémiologie, Monde, Facteur risque, Homme, Incidence, Tumeur maligne, Oeil pathologie, Conjonctive pathologie

    Mots-clés Pascal anglais : Squamous cell carcinoma, Conjunctiva, UVB radiation, Solar radiation, Epidemiology, World, Risk factor, Human, Incidence, Malignant tumor, Eye disease, Conjunctiva disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0271532

    Code Inist : 002B09B. Création : 199608.