Viral infections in short-term injection drug users : The prevalence of the hepatitis C, hepatitis B, human immunodeficiency, and human T-lymphotropic viruses.
The purpose of this study was to estimate the prevalence and correlates of four blood-borne viral infections among illicit drug injectors with up to 6 years of injecting experience.
We analyzed data from 716 volunteers recruited in 1988 and 1989.
Test results for hepatitis C virus (HCV), hepatitis B virus (HBV), human immunodeficiency virus, type 1 (HIV), and human T-lymphotropic virus types I and II (HTLV) were examined across six sequential cohorts defined by duration of drug injection.
Overall, seroprevalence of HCV, HBV, HIV, and HTLV was 76.9%, 65.7%, 20.5% and 1.8%, respectively, and 64.7%, 49.8%, 13.9%, and 0.5%, respectively, among those who had injected for 1 year or less.
Among the newest initiates, HCV and HBV were associated with injecting variables, and HIV was associated with sexual variables.
The high rates of HCV, HBV, and HIV infections among short-term injectors emphasizes the need to target both parenteral and sexual risk reduction interventions early.
Renewed efforts at primary prevention of substance abuse are indicated.
Mots-clés Pascal : Hépatite virale C, Virose, Infection, Hépatite virale B, SIDA, Virus HTLV, Retroviridae, Virus, Epidémiologie, Prévalence, Homme, Transmission, Sang, Toxicomanie, Voie intraveineuse, Etats Unis, Amérique du Nord, Amérique, Appareil digestif pathologie, Foie pathologie, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Viral hepatitis B, AIDS, HTLV virus, Retroviridae, Virus, Epidemiology, Prevalence, Human, Transmission, Blood, Drug addiction, Intravenous administration, United States, North America, America, Digestive diseases, Hepatic disease, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0268010
Code Inist : 002B05C02G. Création : 199608.