Otoneurological study in workers exposed to styrene in the fiberglass industry.
Twenty workers exposed to styrene and acetone in small fiberglass factories were monitored for 8 h using passive dosimeters.
Urine samples were collected at the end of the workshift and before the start of work on the next morning.
The 8-h time-weighted average exposure values for styrene and acetone ranged from 14 to 416 mg/m3 and from 70 to 277 mg/m3, respectively.
The sum of styrene metabolites, mandelic acid and phenylglyoxylic acid (MA+PGA), in the next-morning urine samples ranged from 81 to 943 mg/g creatinine.
Different test sensitivity was identified in the otoneurological battery : it was low for audiometric tests and ABR, and relatively high for vestibular tests.
The vestibular system seems partially sensitive to the toxic effects of styrene in the absence of clinical signs and symptoms.
The actual exposure levels for styrene cannot be considered devoid of functional subclinical consequences.
Mots-clés Pascal : Styrène, Exposition professionnelle, Solvant organique, Acétone, Toxicité, Industrie, Fibre verre, Méthode étude, Système nerveux central pathologie, Diagnostic, Audiométrie, Vestibulométrie, Surveillance biologique, Médecine travail, Système nerveux pathologie, Homme
Mots-clés Pascal anglais : Styrene, Occupational exposure, Organic solvent, Acetone, Toxicity, Industry, Glass fiber, Investigation method, Central nervous system disease, Diagnosis, Audiometry, Vestibulometry, Biological monitoring, Occupational medicine, Nervous system diseases, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0256529
Code Inist : 002B03L04. Création : 199608.