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  1. Fulltext. Relation of breast cancer with passive and active exposure to tobacco smoke.

    Article - En anglais


    Studies on passive smoking have consistently shown a tendency toward an increased risk of breast cancer, while studies on active smoking have failed to demonstrate an association.

    This apparent contradiction may stem from not separating passive smokers from the unexposed when assessing the effect of active smoking.

    A population-based case-control study was conducted in Geneva, Switzerland, between January 1992 and October 1993 to determine the relation of passive and active smoking to breast cancer when the referent unexposed category consisted of women unexposed to active and passive smoke.

    The 244 patients with breast cancer (cases) were compared with 1,032 women free of breast cancer (controls).

    The lifetime history of active and passive smoking was recorded year by year, between the age of 10 years and the date of the interview.

    The adjusted odds ratios of breast cancer for ever active smokers, compared with women unexposed to either passive or active smoke, were 2.2 (95% confidence interval (CI) 1.0-4.4) for an average lifetime consumption of 1-9 cigarettes per day, 2.7 (95% CI 1.4-5.4) for 10-19 cigarettes per day, and 4.6 (95% CI 2.2-9.7) for 20 or more cigarettes per day.

    Among passive smokers, the adjusted odds ratio was 3.2 (95% CI 1.6-6.3) for being exposed for the equivalent of 2 hours per day for 25 years.

    The odds ratios were adjusted for known or postulated risk factors of breast cancer, including alcohol and saturated fat intake.

    There was ...

    Mots-clés Pascal : Tabagisme, Tabagisme passif, Toxicité, Tumeur maligne, Glande mammaire, Suisse, Europe, Epidémiologie, Femme, Homme, Glande mammaire pathologie

    Mots-clés Pascal anglais : Tobacco smoking, Passive smoking, Toxicity, Malignant tumor, Mammary gland, Switzerland, Europe, Epidemiology, Woman, Human, Mammary gland diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0254311

    Code Inist : 002B03E. Création : 199608.