Non-Hodgkin's lymphoma has increased in incidence in many countries, particularly in the West.
Advances in diagnostic methods and the understanding of the disease over time pose a challenge to the interpretation of these trends.
The aim of this study was to determine if the disease has increased in Singapore, a newly industrialized Asian country, and to examine the possible factors that may account for any observed changes.
Data from the population-based Singapore Cancer Registry for the period 1968 to 1992 were reviewed to determine time trends based on sex and ethnic group.
The Poisson regression model was fitted to the cross-tabulated data to obtain the adjusted incidence density ratios.
A total of 1988 cases of non-Hodgkin's lymphoma were included in the analysis.
There was an overall increase in incidence among both Chinese and Malaysians.
However, the rate of increase was greater in females (age-standardized rate from 1.8 per 100,000 in 1968-1972 to 4.5 per 100,000 in 1988-1992) than in males (3.2 per 100,000 to 5.9 per 100,000 in the same time periods).
Between ethnic groups, Malay females were at higher overall risk compared with their Chinese counterparts (incidence density ratio 1.32 ; 95% confidence interval, 1.08-1.61).
Although a substantial proportion of patients diagnosed with Hodgkin's disease between 1968 and 1972 were reclassified on review, using present criteria, as having non-Hodgkin's lymphoma, it is unli...
Mots-clés Pascal : Lymphome non hodgkinien, Homme, Incidence, Epidémiologie, Analyse tendance, Ethnie, Sexe, Singapour, Asie, Hémopathie maligne, Lymphoprolifératif syndrome
Mots-clés Pascal anglais : Non Hodgkin lymphoma, Human, Incidence, Epidemiology, Trend analysis, Ethnic group, Sex, Singapore, Asia, Malignant hemopathy, Lymphoproliferative syndrome
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0253924
Code Inist : 002B19B. Création : 199608.