Despite recognition of the high prevalence of alcoholism among patients with head and neck cancer, the prognostic importance of alcoholism has not been evaluated adequately.
Previous investigators have speculated that alcoholic patients may have a poorer prognosis than nonalcoholic patients because of more advanced stage of cancer, the immunosuppressive effects of alcohol, and an increased rate of death due to other alcohol-related diseases.
The goal of this population-based study was to identify the features of alcoholism that are associated with survival for patients with head and neck cancer and to develop an alcoholic severity staging system from a composite of the independent features of alcoholism.
This prospective study included 649 patients who were diagnosed with cancer of the oral cavity, oropharynx, hypopharynx, or larynx during the period from September 1,1983, through February 28,1987, in a three-county area of western Washington state that participates in the Surveillance, Epidemiology, and End Results Program of the U.S. National Cancer Institute.
Details on lifetime alcohol consumption, treatment for alcoholism, abstinence from alcohol prior to the diagnosis of cancer, and alcohol-related health problems were ascertained through in-person interviews near the time of diagnosis.
Patients were classified as either nonalcoholics or alcoholics according to their responses to questions from the Michigan Alcoholism...
Mots-clés Pascal : Carcinome épidermoïde, Tête cou, Homme, Pronostic, Survie 5 ans, Epidémiologie, Alcoolisme, Echelle évaluation, Indice gravité, Tumeur maligne, ORL pathologie
Mots-clés Pascal anglais : Squamous cell carcinoma, Head and neck, Human, Prognosis, Five year survival, Epidemiology, Alcoholism, Evaluation scale, Severity score, Malignant tumor, ENT disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0246064
Code Inist : 002B10B01. Création : 199608.