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  1. The continuing increase in adenocarcinoma of the uterine cervix : A birth cohort phenomenon.

    Article - En anglais


    Adenocarcinoma of the uterine cervix has been reported to be increasing among young white women and earlier studies suggest a birth cohort pattern for the observed increase.

    No study, however, has examined the time trends of adenocarcinoma of the cervix by birth cohort.


    Using Surveillance, Epidemiology, and End Results (SEER) data through 1990, the current study is designed to examine the time trends of invasive adenocarcinoma by birth cohort.

    An age-period-cohort model was fitted to the annual age-specific rates to identify the components of birth cohort and time period as determinants of the observed time trends.


    The results from this study clearly show that invasive adenocarcinoma of the uterine cervix has been increasing in both whites and blacks but the increase is statistically significant only among whites, reaching 4.2% per year for those born since 1935.

    The results also show that the recent increase in invasive adenocarcinoma started among those born around the mid1920s, and a strong birth cohort effect is largely responsible for the observed increase.


    Invasive adenocarcinoma of the uterine cervix is increasing among recent birth cohorts.

    Analytical epidemiological studies are urgently needed to explore the risk factors responsible for the increase.

    The time trend for adenocarcinoma of the cervix should also be carefully monitored in the coming years.

    Mots-clés Pascal : Adénocarcinome, Col utérus, Incidence, Epidémiologie, Tendance, Evolution, Date naissance, Age, Race, Etats Unis, Amérique du Nord, Amérique, Tumeur maligne, Appareil génital femelle pathologie, Col utérus pathologie

    Mots-clés Pascal anglais : Adenocarcinoma, Uterine cervix, Incidence, Epidemiology, Trend, Evolution, Birth date, Age, Race, United States, North America, America, Malignant tumor, Female genital diseases, Uterine cervix diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0244441

    Code Inist : 002B20C02. Création : 199608.