We reviewed 3 285 consecutive cases of lung cancer diagnosed in West Sweden during the period 1976-1985.
Data were collected from the regional cancer registry, the Swedish National Population Registry, and medical records.
During the study period, the annual female/male ratio increased from 0.29 to 0.42.
In females, there was an increase primarily in the incidence of tobacco-related morphologic tumour types (i.e. squamous and small cell lung cancers).
In males, a moderate increase of adenocarcinomas was seen, although squamous cell cancer remained the most common tumour type.
The overall 5-year survival rate was 8.3%. In 641 patients (20%) a surgical tumour resection was carried out.
The 5-year survival rate following resection was 38%, and the probability of 10-year survival was estimated at 25%. In a multifactorial model including gender, age, histology, pTNM stage and extent of resection, pTNM stage and, to a lesser degree, age were statistically significant independent predictors of postoperative survival.
The five-year survival was 57% in stage I, 21-27% in stage II and IIIa, and 10% in stage IIIb.
Of all resected patients, 4.2% died within two months after resection.
In males, early postoperative mortality was predicted by preoperative bicycle ergometry.
The prognosis in non-resected patients was poor, with only 2% surviving 5 years or longer.
In conclusion, the results indicate that some progress has been made with regard to surgical management of l...
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Incidence, Epidémiologie, Chirurgie, Traitement, Pronostic, Mortalité, Etude longitudinale, Suède, Europe, Ouest, Homme, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Incidence, Epidemiology, Surgery, Treatment, Prognosis, Mortality, Follow up study, Sweden, Europe, West, Human, Respiratory disease, Lung disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0239728
Code Inist : 002B11A. Création : 199608.