Racial differences in survival of female breast cancer in the Detroit Metropolitan area.
In the United States, breast cancer survival is worse among African-American women compared with white women.
This difference in survival is likely due to several factors, including tumor biology and/or access to care.
In this analysis, we evaluated the effects of sociodemographic and clinical variables on differences in breast cancer survival among African-American and white women.
The study population included 10,502 women (82% white, 18% African-American), diagnosed between 1988 and 1992 and identified through the Metropolitan Detroit Cancer Surveillance System, a member of the Surveillance, Epidemiology and End-Results (SEER) Program.
Cox proportional hazards regression was used to estimate the relative risk of death comparing African-American women with white women after controlling for variables believed to influence survival.
The mean age at diagnosis was 61 years and average length of follow-up was 34 months (range, 1-78 months).
African-American women were more likely to present with regional or distant disease (45%) than were white women (37%). Although white women had better survival than African-American women during the first 4 years postdiagnosis (P<0.0001), there were no significant differences in survival by race for women who lived longer than 4 years (P=0.64).
There was a significant interaction between age and race.
The unadjusted relative risk of dying for African-American women compared with white women wa...
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Homme, Caucasoïde, Négroïde, Femelle, Pronostic, Survie, Etude comparative, Epidémiologie, Zone urbaine, Michigan, Etats Unis, Amérique du Nord, Amérique, Noir américain, Glande mammaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Human, Caucasoid, Negroid, Female, Prognosis, Survival, Comparative study, Epidemiology, Urban area, Michigan, United States, North America, America, Black American, Mammary gland diseases
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0238177
Code Inist : 002B20E02. Création : 199608.