Obstetric complications and schizophrenia : A case control study based on standardised obstetric records.
There have been many reports of a higher incidence of bbstetric complications'in the histories of schizophrenics than of controls, but because of the methodological shortcomings of most of these comparisons the relationship remains controversial.
Comprehensive records covering all psychiatric hospital admissions and all hospital deliveries in Scotland since 1971 made it possible to identify the obstetric records of people born in 1971-74 who were subsequently admitted to hospital with a diagnosis of schizophrenia, and then to compare their standardised obstetric records with those of closely matched controls.
One hundred and fifteen schizophrenic/control pairs were compared.
The former showed a highly significant (P<0.001) excess of complications of both pregnancy and delivery.
In particular, there was a significant excess of pre-eclampsia (10 v. 2) and of infants detained in hospital for neonatal care (18 v. 6).
The raised incidence of obstetric complications often reported in people with schizophrenia is genuine and probably contributes to the aetiology of the condition.
Mots-clés Pascal : Schizophrénie, Psychose, Etiologie, Complication, Accouchement pathologie, Gestation pathologie, Etude longitudinale, Ecosse, Grande Bretagne, Royaume Uni, Europe, Dossier médical, Homme
Mots-clés Pascal anglais : Schizophrenia, Psychosis, Etiology, Complication, Delivery disorders, Pregnancy disorders, Follow up study, Scotland, Great Britain, United Kingdom, Europe, Medical record, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0233454
Code Inist : 002B18C06A. Création : 199608.