Background There have been very few reports of occupational allergies caused by inhalation of buckwheat flour.
In this paper, we present a case of occupational asthma and rhinitis caused by buckwheat flour inhalation.
Methods and results The patient had strong positive responses to grass and ragweed pollens as well.
The bronchoprovocation test showed early asthmatic response to buckwheat flour extracts.
Serum specific IgE antibody to buckwheat flour was detected by enzyme-linked immunosorbent assay (ELISA).
In order to further identify the allergenic component of the extracts, sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and electroblotting studies were performed.
Eight IgE binding components (9-55 kDa) were detected within the buckwheat flour extracts.
Conclusion These results suggest that inhalation of buckwheat flour can caused IgE mediated bronchoconstriction.
Mots-clés Pascal : Asthme, Etiologie, Rhinite, Allergie, Exposition professionnelle, Fagopyrum esculentum, Polygonaceae, Dicotyledones, Angiospermae, Spermatophyta, Sarrasin, Farine blé, Etude cas, Corée, Asie, Adulte jeune, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, ORL pathologie, Nez pathologie, Immunopathologie, Maladie professionnelle, Médecine travail
Mots-clés Pascal anglais : Asthma, Etiology, Rhinitis, Allergy, Occupational exposure, Fagopyrum esculentum, Polygonaceae, Dicotyledones, Angiospermae, Spermatophyta, Buck wheat, Wheat flour, Case study, Korea, Asia, Young adult, Human, Respiratory disease, Obstructive pulmonary disease, ENT disease, Nose disease, Immunopathology, Occupational disease, Occupational medicine
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0219656
Code Inist : 002B06C02. Création : 199608.