The purpose of this case-control investigation was to investigate the possible association between mild-to-moderate enamel fluorosis and exposure during early childhood to fluoride supplements, fluoride toothpaste, and/or infant formula use in nonfluoridated communities.
Analysis was performed on 460 10-to 13-year-old children, born after 1979, who were residents of six nonfluoridated communities in Massachusetts and Connecticut.
The fluorosis status of the subjects was determined on the basis of a clinical dental examination using the Fluorosis Risk Index (FRI).
Risk factor exposure was ascertained via a mailed questionnaire with a response rate of 90% and a questionnaire reliability of 87%. Logistic regression analyses revealed a moderate association between mild-to-moderate enamel fluorosis on early forming (FRI classification I) enamel surfaces and both fluoride supplement use (odds ratio (OR)=2.25,95% confidence interval (Cl) 1.08-4.69) and early toothbrushing habits (OR=2.56,95% CI 1.34-4.88).
There was a strong association between mild-to-moderate fluorosis on later forming (FRI classification II) enamel surfaces and both supplement use (OR=7.97,95% Cl 2.98-21.33) and early toothbrushing habits (OR=4.23,95% CI 1.72-10.41).
Infant formula was not found to be associated with fluorosis on either FRI classification I or II surfaces.
Mots-clés Pascal : Fluorose, Email dentaire, Epidémiologie, Fluor, Supplémentation, Dentifrice, Lait infantile, Enfant, Homme, Toxicité, Connecticut, Etats Unis, Amérique du Nord, Amérique, Massachusetts, Dent pathologie
Mots-clés Pascal anglais : Fluorosis, Tooth enamel, Epidemiology, Fluorine, Supplementation, Toothpaste, Infant formula, Child, Human, Toxicity, Connecticut, United States, North America, America, Massachusetts, Dental disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0218154
Code Inist : 002B03L05. Création : 199608.