A case of hantavirus pulmonary syndrome with possible exposure in New York and/or Rhode Island was confirmed in February 1994.
To conduct four studies to determine the historical and geographic distribution of human and small-mammal infection with hantaviruses in New York State.
Enzyme-linked immunosorbent assays were performed on serum samples obtained from 130 humans during a 1978 babesiosis survey, 907 small mammals collected in New York State since 1984,12 rodents collected in 1994 near the residences of the patients with hantavirus pulmonary syndrome, and 76 New York patients with acute respiratory distress syndrome-like illness (as suspected cases of hantavirus pulmonary syndrome).
None of the human serum samples from the 1978 serosurvey showed evidence of hantavirus exposure by enzyme-linked immunosorbent assay.
State-wide historical serum samples from white-footed mice showed evidence of Sin Nombre virus infection in 12.0% (97/809) and Seoul-like virus infection in 9.6% (78/809).
Site-specific seropositivity rates were as high as 48.5% with Sin Nombre virus during 1 year (1984).
Two of 12 mice captured near the residences of a human patient were positive for Sin Nombre virus by enzyme-linked immunosorbent assay, yet were negative for viral RNA by polymerase chain reaction.
None of the patients with suspected hantavirus pulmonary syndrome was serologically reactive for Sin Nombre virus.
Mots-clés Pascal : Hantavirus, Bunyaviridae, Virus, Insuffisance pulmonaire, Homme, Poumon pathologie, Animal, Etats Unis, Amérique du Nord, Amérique, Virose, Infection, Appareil respiratoire pathologie
Mots-clés Pascal anglais : Hantavirus, Bunyaviridae, Virus, Pulmonary regurgitation, Human, Lung disease, Animal, United States, North America, America, Viral disease, Infection, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0216369
Code Inist : 002B05C02C. Création : 199608.