Objective To use the linked medical and death records in Scotland to investigate the possible increased mortality that has been reported after transurethral prostatectomy (TURP) compared with open prostatectomy.
Patients and methods Scotland has maintained linkable hospital, cancer and death records for more than 20 years, representing one of the largest such databases in the world.
From these computerized records, data on various cohorts of men aged 55-84 years selected from 81 997 men who underwent prostatectomy in Scotland between 1968 and 1989 were analysed.
The risk of late mortality was calculated for each type of operation, whether there was prior comorbidity and for a range of specific causes (cancer, respiratory and circulatory conditions) after prostatectomy.
Results Among the largest cohort, consisting of 65 519 men who underwent prostatectomy between 1968 and June 1989, the relative risk of late mortality after TURP compared with open prostatectomy was 1.13 (95% CI, 1.10-1.16), after controlling for age and the presence of a diagnosis of cancer.
A more restricted cohort of 18 732 men who underwent prostatectomy between 1974 and 1979 allowed adjustment for prior hospitalization with, or concurrent diagnosis of, circulatory and respiratory conditions.
In this cohort, the relative risk of late mortality after TURP as compared with open prostatectomy was 1.15 (95% CI, 1.11-1.19) after adjusting for prior and comorbidity and age.
Finally, a cohort o...
Mots-clés Pascal : Mortalité, Epidémiologie, Ecosse, Grande Bretagne, Royaume Uni, Europe, Etude comparative, Complication, Prostatectomie, Voie abord, Chirurgie endoscopique, Voie percutanée, Mâle, Homme, Chirurgie, Appareil urinaire pathologie
Mots-clés Pascal anglais : Mortality, Epidemiology, Scotland, Great Britain, United Kingdom, Europe, Comparative study, Complication, Prostatectomy, Surgical approach, Endoscopic surgery, Percutaneous route, Male, Human, Surgery, Urinary system disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0216052
Code Inist : 002B25H. Création : 199608.