Changes in the localization of colorectal cancer : Implications for clinical practice.
A hospital-based study was performed in order to examine the subsite distribution of colorectal cancer diagnosed in 1992-93 in the Zaanstreek region.
The localization was compared with tumours diagnosed in the years 1972-73 and 1982-83.
The number of colorectal cancers has markedly increased, and a significant rise in localization of tumours proximal to the splenic flexure has occurred (32% in 1972-73 to 43% in 1992-93).
There also appears to be greater incidence of colorectal cancer in women.
A trend towards an increase of proximal localization of tumours in women was noted.
Possible explanations for this phenomenon are discussed.
The results of this study suggest the importance of improved diagnostic accuracy in colorectal cancer and, in addition, may have consequences for screening programmes.
Mots-clés Pascal : Carcinome, Côlon, Rectum, Localisation, Variation temporelle, Etude comparative, Homme, Pays Bas, Europe, Tumeur maligne, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie
Mots-clés Pascal anglais : Carcinoma, Colon, Rectum, Localization, Time variation, Comparative study, Human, Netherlands, Europe, Malignant tumor, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0203742
Code Inist : 002B13B01. Création : 199608.