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  1. Predictors of survival in patients receiving domiciliary oxygen therapy or mechanical ventilation : A 10-year analysis of ANTADIR observatory.

    Article - En anglais

    Study objective 

    To analyze predictors of survival for patients receiving home long-term oxygen therapy (LTOT) or prolonged mechanical ventilation (PMV) according to the cause of chronic respiratory insufficiency (CRI) and the patient's physiologic data.


    Analysis of a nationwide database (ANTADIR Observatory).


    The national nonprofit network for home treatment of patients with CRI Association Nationale pour le Traitement à Domicile de l'Insuffisance Respiratoire Chronique (ANTADIR) : founded in France in the 1980s.


    There were 26,140 patients receiving LTOT or PMV (noninvasive or via tracheostomy) between January 1,1984 and January 1,1993 (chronic bronchitis, 12,043 ; asthma, 1,755 ; bronchiectasis, 1,556 ; emphysema, 551 ; tuberculosis sequelae, 4,147 ; kyphoscoliosis, 1,574 ; neuromuscular diseases, 1,097 ; pneumoconiosis, 919 ; and fibrosis, 2,498).

    Measurements and results 

    Survival analysis was performed using the actuarial and the Cox's semiparametric model.

    The mean survival for patients with chronic bronchitis is 3 years.

    Survival is slightly better for patients with bronchiectasis and asthma and worse for those with emphysema.

    Patients with kyphoscoliosis and a neuromuscular disease have the longest survival (8 and 6.5 years, respectively).

    Patients with CRI due to tuberculosis sequelae experience the same survival as COPD patients (3 years).

    Prognosis is the worst in patients with pneumoconiosis or fibrosis : 50% of ...

    Mots-clés Pascal : Insuffisance respiratoire, Chronique, Homme, Pronostic, Survie, A domicile, Oxygénothérapie, Ventilation mécanique, Réseau observation, Base donnée, France, Europe, Traitement, Epidémiologie, Appareil respiratoire pathologie, Soin intensif, Ventilation artificielle

    Mots-clés Pascal anglais : Respiratory failure, Chronic, Human, Prognosis, Survival, At home, Oxygenotherapy, Mechanical ventilation, Observational network, Database, France, Europe, Treatment, Epidemiology, Respiratory disease, Intensive care, Artificial ventilation

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0199728

    Code Inist : 002B11D. Création : 199608.