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  1. Developmental effects of dioxins and related endocrine disrupting chemicals.

    Article, Communication - En anglais

    International Congress of Toxicology. Seattle, Washington USA, 1995/07/02.

    Alteration of hormones has long been known to affect development.

    TCDD and related PHAHs modulate the levels of many hormonal systems.

    Dioxins cause a spectrum of morphological and functional developmental deficits.

    Fetotoxicity, thymic atrophy, and structural malformations are often noted.

    Delayed genitourinary tract effects have been observed, and recent studies reported behavioral effects.

    Highly exposed human offspring have exhibited developmental problems as well.

    Recently, hormonal and neurological abnormalities have been reported in infants from the general population.

    The complex alteration of multiple endocrine systems is likely associated with the spectrum of adverse developmental effects caused by dioxin and related compounds.

    Mots-clés Pascal : Dibenzo-p-dioxine(2,3,7,8-tétrachloro), Composé aromatique polycyclique, Biphényle(polychloro), Toxicité, Endocrinopathie, Reproduction pathologie, Sécrétion endocrine, Homme, Nourrisson, Tératogène, Hormone, Animal, Polluant, Environnement

    Mots-clés Pascal anglais : Polycyclic aromatic compound, Polychlorobiphenyl, Toxicity, Endocrinopathy, Reproduction diseases, Endocrine secretion, Human, Infant, Teratogen, Hormone, Animal, Pollutant, Environment

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0183646

    Code Inist : 002B03M01. Création : 199608.