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  1. MMR vaccination, measles epidemiology and sero-surveillance in the Republic of Ireland.

    Article - En anglais

    Objective

    Following the introduction of a national measles and subsequent MMR vaccination programme, to determine the susceptibility of 3-14-year-old children to measles, mumps and rubella and to relate the results to the epidemiology of measles and the need for vaccination policy changes.

    Design-Cross-sectional sero-survey and trends in measles notifications and mortality.

    Setting-Paediatric hospital outpatient departments in Dublin.

    Subjects-Sera were collected from 837 children attending the clinics in 1991 and 1992.

    Results

    The prevalence of antibodies in children aged 3-6,7-10 and 11-14 years was 84,83 and 95% for measles ; 48,60 and 65% for mumps ; and 78,63 and 74% for rubella, respectively.

    The prevalence of mumps antibodies may be underestimated.

    Ninety-six per cent of girls aged 13-14 years had rubella antibodies.

    A widespread outbreak of measles occurred in 1993.

    Over recent years, an increasing proportion of measles notifications were in older children.

    Conclusion-Given sub-optimal uptake of MMR vaccine, outbreaks of infection in pre-and primary school children are inevitable.

    In such circumstances, a 2-shot MMR vaccine programme with high uptake is essential to prevent a shit of disease into older age groups.

    Mots-clés Pascal : Vaccination, Rougeole, Virose, Infection, Oreillons, Rubéole, Epidémiologie, Virus rougeole, Morbillivirus, Paramyxoviridae, Virus, Santé publique, Sérologie, Enfant, Homme, Irlande, Europe

    Mots-clés Pascal anglais : Vaccination, Measles, Viral disease, Infection, Mumps, Rubella, Epidemiology, Measles virus, Morbillivirus, Paramyxoviridae, Virus, Serology, Child, Human, Ireland, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0174889

    Code Inist : 002B05A02. Création : 199608.