Self-reported stress and risk of breast cancer.
Many women attribute the development of their breast cancer to psychosocial factors such as stress and depression.
Yet investigations of the relationship between breast cancer and stressful life events have had inconsistent outcomes, due in part to studies with small sample sizes and reliance on hospital-based populations.
As part of a population-based, case-control study of breast cancer etiology, we evaluated the association between stressful life events and the risk of breast cancer among 258 breast cancer patients and 614 randomly selected population-based controls.
Information on 11 stressful life events was collected in telephone interviews with women aged 50-79 who were participating in the ongoing study.
Breast cancer patients and controls experienced the same number of stressful life events in the five years prior to diagnosis or an equivalent reference date (controls), averaging 2.4 and 2.6 events, respectively.
After adjustment for known breast cancer risk factors, there was no association between weighted stressful life event scores and the risk of breast cancer (odds ratio epsilonORzêta=0.90 per unit increase ; 95% confidence interval epsilonCIzêta, 0.78-1.05).
Only one life event, death of a close friend, was significantly more often reported by controls (OR=0.72 ; 95% CI, 0.52-1.00).
Other life events were inconsistently and nonsignificantly associated with breast cancer risk.
The results of this re...
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Epidémiologie, Facteur risque, Stress, Evénement existentiel, Homme, Femelle, Glande mammaire pathologie, Santé publique
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Epidemiology, Risk factor, Stress, Life events, Human, Female, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0174855
Code Inist : 002B20E02. Création : 199608.