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  1. Arsenic burden among children in industrial areas of eastern Germany.

    Article - En anglais

    The internal burden of arsenic among 5-to 14-year-old eastern German children in the heavily polluted areas of Hettstedt, a region of smelting and copper mining, and Bitterfeld, a center of chemical production and coal mining, was compared with that in a control area (Zerbst) by means of urinary arsenic concentrations in 1992-94.

    The unadjusted geometric mean among the 950 children was significantly higher in Hettstedt (5.1 ƒg/l ; 95% C.I. 4.8-5.5) but not in Bitterfeld (4.3 ƒg/l ; 95% C.I. 3.7-4.9) compared with the control area (4.0 ƒg/l ; 95% C.I. 3.5-4.5).

    This difference persisted after adjustment for relevant confounders.

    Despite these regional differences, recent fish consumption was as strongly associated with urinary arsenic levels (42% increase, 95% C.I. 18-71%). Additionally, although the geometric mean among the children in Hettstedt (4.8 ƒg As/g creatinine ; 95% C.I. 4.5-5.1) was higher than that found in an environmental survey of eastern German children (3.60 ƒg As/g creatinine ; 95% C.I. 3.06-4.24), it was similar to that found among western German children (4.59 ƒg As/g creatinine ; 95% C.I. 4.20-5.02).

    This suggests that the arsenic contamination in Hettstedt is not substantially increasing the internal burden of arsenic among children above that found in other German children.

    Mots-clés Pascal : Arsenic, Métal lourd, Polluant, Environnement, Epidémiologie, Enfant, Homme, Urine, Taux, Surveillance biologique, Santé publique, Est, Allemagne, Europe, Zone industrielle

    Mots-clés Pascal anglais : Arsenic, Heavy metal, Pollutant, Environment, Epidemiology, Child, Human, Urine, Rate, Biological monitoring, East, Germany, Europe, Industrial area

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0174484

    Code Inist : 002B03M01. Création : 199608.