The internal burden of arsenic among 5-to 14-year-old eastern German children in the heavily polluted areas of Hettstedt, a region of smelting and copper mining, and Bitterfeld, a center of chemical production and coal mining, was compared with that in a control area (Zerbst) by means of urinary arsenic concentrations in 1992-94.
The unadjusted geometric mean among the 950 children was significantly higher in Hettstedt (5.1 g/l ; 95% C.I. 4.8-5.5) but not in Bitterfeld (4.3 g/l ; 95% C.I. 3.7-4.9) compared with the control area (4.0 g/l ; 95% C.I. 3.5-4.5).
This difference persisted after adjustment for relevant confounders.
Despite these regional differences, recent fish consumption was as strongly associated with urinary arsenic levels (42% increase, 95% C.I. 18-71%). Additionally, although the geometric mean among the children in Hettstedt (4.8 g As/g creatinine ; 95% C.I. 4.5-5.1) was higher than that found in an environmental survey of eastern German children (3.60 g As/g creatinine ; 95% C.I. 3.06-4.24), it was similar to that found among western German children (4.59 g As/g creatinine ; 95% C.I. 4.20-5.02).
This suggests that the arsenic contamination in Hettstedt is not substantially increasing the internal burden of arsenic among children above that found in other German children.
Mots-clés Pascal : Arsenic, Métal lourd, Polluant, Environnement, Epidémiologie, Enfant, Homme, Urine, Taux, Surveillance biologique, Santé publique, Est, Allemagne, Europe, Zone industrielle
Mots-clés Pascal anglais : Arsenic, Heavy metal, Pollutant, Environment, Epidemiology, Child, Human, Urine, Rate, Biological monitoring, East, Germany, Europe, Industrial area
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0174484
Code Inist : 002B03M01. Création : 199608.