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  1. Male breast cancer in Iceland.

    Article - En anglais

    All malignant tumours of the male breast diagnosed in Iceland during the 40-year period 1955-1994 were studied with regard to histological classification, tumour grading and flow cytometric analysis.

    Of 31 malignant tumours diagnosed, 29 were primary breast carcinomas.

    Male breast carcinoma constitutes 1% of all breast malignancies in Iceland and 0.25% of all malignant tumours in males.

    About 80% of the male breast carcinomas were diagnosed during the latter half of the study period.

    The mean age of the patients was 66.3 years and the left-to-right ratio was 1.9 : 1.0. Right-sided tumours appeared to be more aggressive.

    The mean tumour size was 2.6 cm.

    The vast majority of the carcinomas (79%) were of the infiltrating ductal type.

    Of these 21.7% were grade 1,43.5% were grade II and 34.8% grade III.

    Papillary carcinomas made up 17% of the total.

    These occurred in slightly older patients than the infiltrating ductal carcinomas and were diploid tumours.

    In this study 57% of the tumours were found to be aneuploid, but nearly 70% of the invasive ductal carcinomas NOS were aneuploid.

    In general, the aneuploid tumours were larger, of higher average histological grade and had a higher mean S-phase value.

    The overall mean S-phase fraction was 7.2% which is similar to that found in female breast tumours in Iceland.

    It is concluded that the male-to-female ratio of breast carcinoma in Iceland is similar to that found in other Western countries.

    The age-standardised in...

    Mots-clés Pascal : Carcinome, Glande mammaire, Homme, Mâle, Epidémiologie, Histopathologie, Type histologique, Grade histologique, Cytométrie flux, Ploi`die, Islande, Iles Atlantiques, Tumeur maligne, Glande mammaire pathologie, Anatomopathologie, Santé publique

    Mots-clés Pascal anglais : Carcinoma, Mammary gland, Human, Male, Epidemiology, Histopathology, Histological type, Histological grading, Flow cytometry, Ploidy, Iceland, Atlantic Ocean Islands, Malignant tumor, Mammary gland diseases, Pathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0152720

    Code Inist : 002B20E02. Création : 199608.