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  1. Passive smoking in children : racial differences in systemic exposure to cotinine by hair and urine analysis.

    Article - En anglais

    Passive smoking has been shown to adversely affect the health of infants and children.

    Black children and adults appear to be more susceptible to a variety of tobacco smoke health hazards for unknown reason.

    The objectives of this study were as follows : (1) to correlate the number of cigarettes reported to have been smoked by parents with urine and hair concentrations of cotinine in children ; and (2) to identify race differences in systemic exposure to cotinine in children.

    This was an observational study in a consulting pediatric office on 169 nonsmoking children between 2 and 18 years of age, not actively smoking.

    The outcome measures of interest were urinary cotinine concentrations corrected for milligram of creatinine and hair concentration of cotinine (per milligram of hair).

    There were significant correlations between the number of cigarettes the child was exposed to and urinary cotinine (r=0.68, p=0.0001) or hair cotinine concentrations (r=0.19, p=0.02), and between urinary and hair cotinine (r=0.3, p=0.0005).

    In this cohort, parents of black children (n=21) tended to smoke less (6.6rhô3/d, meanrhôSEM) than white parents (n=97) (12rhô1,8, meanrhôSEM) (p=0.2).

    Despite being exposed to less cigarettes, black children had higher hair concentrations of cotinine than white children (0.89 rhô0.25 ng/mg vs 0.48rhô0.05 ng/mg ; p=0.05).

    The ratio hair/urine concentrations of cotinine was twofold higher in black children (0.035rhô0.01 vs 0.019rhô0.002 ; p=0...

    Mots-clés Pascal : Tabagisme passif, Enfant, Facteur risque, Race, Etude comparative, Urine, Cheveu, Analyse biochimique, Cotinine, Homme, Santé publique

    Mots-clés Pascal anglais : Passive smoking, Child, Risk factor, Race, Comparative study, Urine, Hair (head), Biochemical analysis, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0152431

    Code Inist : 002B30A03B. Création : 199608.