Effects of national cholesterol education program step 2 diets relatively high or relatively low in fish-derived fatty acids on plasma lipoprotein in middle-aged and elderly subjects.
The effects of two National Cholesterol Education Program (NCEP) Step 2 diets (iota 30% of energy as total fat,<7% of energy as saturated fat, and<200 mg cholesterol/d), one relatively high and the other relatively low in fish-derived fatty acids, on plasma lipoprotein concentrations and blood pressure were compared in 22 men and women with a mean (rhô SD) age of 63 rhô 10 y. Subjects were placed on a baseline diet similar to the diet currently consumed in the United States (35% of energy as total fat, 14% of energy as saturated fat, 35 mg cholesterol/MJ) for 6 wk and then on either an NCEP Step 2 diet relatively high in fish (Step 2 high-fish, n=11) or relatively low in fish (Step 2 low-fish, n=11) for 24 wk.
All food and drinks were provided.
Compared with baseline values, consumption of both the Step 2 high-fish and the Step 2 low-fish diets under weight-stable conditions was associated with significant decreases in plasma concentrations of total cholesterol (-14% and - 19%, respectively), low-density-lipoprotein (LDL) cholesterol (-15% and - 20%, respectively), and high-density-lipoprotein (HDL) cholesterol (-11% and - 17%, respectively).
Postprandial, but not fasting, triacylglycerol concentrations were significantly reduced during consumption of the Step 2 high-fish diet.
There were no significant changes in these indexes after consumption of the Step 2 low-fish diet compared with the baseline diet.
LDL particle size decreased significantly (-12%) on...
Mots-clés Pascal : Vieillard, Homme, Adulte, Programme sanitaire, Régime alimentaire, Acide gras n-3, Huile poisson, Cholestérolémie, Lipoprotéine, Santé publique, Education nutritionnelle, Lipide, Lipémie, Nutrition, Alimentation, Etats Unis, Amérique du Nord, Amérique
Mots-clés Pascal anglais : Elderly, Human, Adult, Sanitary program, Diet, n-3 fatty acid, Fish oil, Cholesterolemia, Lipoprotein, Nutrition education, Lipids, Lipemia, Nutrition, Feeding, United States, North America, America
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0150838
Code Inist : 002B29B. Création : 199608.