Use of the Centers for Disease Control and Prevention Childhood lead poisoning risk questionnaire to predict blood lead elevations in pregnant women.
To assess the accuracy of a questionnaire developed by the Centers for Disease Control and Prevention (CDC), given to pregnant women for identification of children at risk for lead poisoning.
The study population consisted of all 314 new prenatal patients enrolled in health department clinics in 1990-1992.
Lead was measured in venous blood, and patients completed written questionnaires to gather information about lead exposure risk factors.
The relationship between elevated maternal blood lead levels (at or greater than 10 g/dL or 0.483 mol/L) and responses to the CDC questionnaire and other questions were examined using xi#F2 statistical analysis.
Two hundred ninety-nine women provided responses to questions about lead exposure risk.
Thirty-nine women (13%) had elevated blood lead levels.
A woman with a positive response to at least one CDC question was more likely to have elevated blood lead than a woman who answered negatively to all four CDC questions (relative risk=2.39,95% confidence interval 1.17-4.89 ; P=01).
Using the CDC definition of high risk ( « yes » to at least one question), the questionnaire had a sensitivity of 75.7% and a negative predictive value of 93.1%. A questionnaire that combined housing conditions, smoking status, and high consumption of canned foods had a sensitivity of 89.2% and a negative predictive value of 96.4%. A high prevalence of elevated blood lead in children living with women with elevat...
Mots-clés Pascal : Intoxication, Eau alimentation, Plomb, Toxicité, Facteur risque, Gestation, Mère, Homme, Femelle, Dosage, Sang, Prévention, Enfant, Médecine préventive, Santé publique, Surveillance, Etude cohorte
Mots-clés Pascal anglais : Poisoning, Feed water, Lead, Toxicity, Risk factor, Pregnancy, Mother, Human, Female, Assay, Blood, Prevention, Child, Preventive medicine, Surveillance, Cohort study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0148621
Code Inist : 002B03H. Création : 199608.