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  1. Menstrual and reproductive factors and risk of breast cancer in Asian-Americans.

    Article - En anglais

    We conducted a population-based case-control study of breast cancer among Chinese-Japanese-and Filipino-American women in Los Angeles County Metropolitan Statistical Area (MSA), San Francisco-Oakland MSA and Oahu, Hawaii.

    One objective of the study was to quantify breast cancer risks in relation to menstrual and reproductive histories in migrant and US-born Asian-Americans and to establish whether the gradient of risk in Asian-Americans can be explained by these factors.

    Using a common study design and questionnaire in the three study areas, we successfully conducted in-person interviews with 597 Asian-American women diagnosed with incident, primary breast cancer during the period 1983-87 (70% of those eligible) and 966 population-based controls (75% of those eligible).

    Controls were matched to cases on age, ethnicity and area of residence.

    In the present analysis, which included 492 cases and 768 controls, we observed a statistically non-significant 4% reduction in risk of breast cancer with each year delay in onset of menstruation.

    Independent of age at menarche risk of breast cancer was lower (odds ratio ; OR=0.77) among women with menstrual cycles greater than 29 days.

    Parous Asian-American women showed a significantly lower risk of breast cancer than nulliparous women (OR=0.54).

    An increasing number of livebirths and a decreasing age at first livebirth were both associated with a lower risk of breast cancer, although the effect of number of livebirths...

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Epidémiologie, Menstruation, Reproduction, Parité, Asiatique, Etats Unis, Amérique du Nord, Amérique, Homme, Glande mammaire pathologie, Santé publique, Etude cas témoin

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Epidemiology, Menstruation, Reproduction, Parity, Asiatic, United States, North America, America, Human, Mammary gland diseases, Case control study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0144921

    Code Inist : 002B20E02. Création : 199608.