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  1. Childhood cancer in the United States : a geographical analysis of cases from the pediatric cooperative clinical trials groups.

    Article - En anglais


    After injuries, cancer is the leading cause of death in children younger than 15 years in the United States.

    Despite dramatic increases in 5-year survival rates, more than 100,000 person-years of life are lost to childhood cancer each year.

    The exact proportion of pediatric cancer patients who receive care at centers that utilize up-to-date therapeutic protocols epsilonsuch as those affiliated with the Childrens Cancer Group (CCG) or the Pediatric Oncology Group (POG) zêta remains unknown.

    The purpose of this study was to estimate the proportion and geographic distribution of childhood cancer patients in the United States who are seen at participating centers of the CCG and the POG.


    Patients included 21,026 incident pediatric cancer cases diagnosed from January 1,1989 through December 31,1991.

    Observed numbers of pediatric cancer cases were compared with expected numbers of cases calculated from incidence rates obtained from the Surveillance, Epidemiology, and End Results (SEER) Program and population counts obtained from the 1990 U.S. Census Bureau.


    Approximately 94% of children younger than 15 years diagnosed with cancer are seen at an institution that is a member of either POG or CCG.

    Comparisons of the observed-to-expected numbers of incident cases in the age groups (birth-4 years, 5-9 years, 10-14 years, and 15-19 years) demonstrated ascertainment rates of 100,93,84, and 21%, respectively.

    In some regions within the Unite...

    Mots-clés Pascal : Lymphome, Tumeur maligne, Répartition géographique, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Enfant, Homme, Hémopathie maligne, Lymphoprolifératif syndrome, Santé publique

    Mots-clés Pascal anglais : Lymphoma, Malignant tumor, Geographic distribution, Epidemiology, United States, North America, America, Child, Human, Malignant hemopathy, Lymphoproliferative syndrome

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0142846

    Code Inist : 002B04B. Création : 199608.