logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. The results of a five-year early prostate cancer detection intervention.

    Article - En anglais

    BACKGROUND

    The American Cancer Society-National Prostate Cancer Detection Project (ACS-NPCDP) is a multidisciplinary evaluation of early prostate cancer detection interventions.

    This report summarizes the experience of the investigators to date and describes the overall and relative performance of the different detection modalities studied in this project.

    METHODS

    Two thousand nine hundred ninety-nine men aged 55 to 70 years at entry who were not already under evaluation for prostate cancer were recruited to participate in up to 5 annual examinations by prostate specific antigen (PSA), digital rectal examination (DRE), and transrectal ultrasound (TRUS).

    In the course of 5 years of intervention, ACS-NPCDP investigators have completed 9937 examinations, recommended 1215 biopsies, and detected 203 cancers.

    RESULTS

    Loss to cohort follow-up was greatest in the first year.

    Overall, TRUS led to twice the number of recommendations for biopsy compared with DRE (8.9% versus 4.4%). Elevated PSA was observed in 13.0% of 9535 measurements performed.

    The overall cancer detection rate declined significantly during the five years of intervention.

    Detection was significantly associated with age and symptom status at entry.

    DRE had lower sensitivity compared with TRUS or PSA, particularly in later years of follow-up.

    The specificity of TRUS was lower than that for DRE.

    PSA was elevated in 69.2% of examinations that led to cancer detection, compared with only 10.9% when c...

    Mots-clés Pascal : Tumeur maligne, Prostate, Dépistage, Diagnostic, Antigène spécifique prostate, Marqueur tumoral, Toucher rectal, Echographie, Rectum, Exploration ultrason, Etats Unis, Amérique du Nord, Amérique, Homme, Appareil génital mâle pathologie, Appareil urinaire pathologie, Prostate pathologie, Santé publique

    Mots-clés Pascal anglais : Malignant tumor, Prostate, Medical screening, Diagnosis, Prostate specific antigen, Tumoral marker, Rectal touch, Echography, Rectum, Sonography, United States, North America, America, Human, Male genital diseases, Urinary system disease, Prostate disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0141087

    Code Inist : 002B14D02. Création : 199608.