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  1. Increased variability in bronchial responsiveness in aluminum potroom workers with work-related asthma-like symptoms.

    Article - En anglais

    In a longitudinal study, we studied the variability in bronchial responsiveness (BR) to methacholine in aluminum potroom workers suffering from work-related asthma-like symptoms (WASTH) and in symptom-free workers.

    In the index group, 26 men suffering from WASTH were selected from a cross-sectional survey.

    The reference group comprised 45 symptom-free men recruited from the enrollment of new employees.

    Bronchial responsiveness was expressed as the dose-response slope (DRS) of the line through origin and the last data point.

    The standard deviation of the log-transformed DRS was positively associated with symptom score (P=012) and the mean BR (P<. 001).

    Our results indicate that the severity of respiratory symptoms in aluminum potroom workers with WASTH reflects the variability in BR.

    Mots-clés Pascal : Fonderie, Four pot, Aluminium, Exposition professionnelle, Homme, Test provocation, Toxicité, Médecine travail, Poumon pathologie, Appareil respiratoire pathologie, Asthme like

    Mots-clés Pascal anglais : Foundry, Pot furnace, Aluminium, Occupational exposure, Human, Provocation test, Toxicity, Occupational medicine, Lung disease, Respiratory disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0122948

    Code Inist : 002B03L05. Création : 199608.