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  1. Evolution of drug resistance in Salmonella panama isolates in Chile.

    Article - En anglais

    In a search for Salmonella isolates in the environment in Chile in 1975, drug-susceptible strains of Salmonella panama were recovered for the first time from river water and vegetables in the vicinity of Santiago.

    Two to 3 years later, antibiotic-resistant S. panama began to appear in a variety of sources (meat, animals, vegetables, etc.), giving rise to a human epidemic that involved the entire nation.

    Of 139 clinical isolates studied, 7 were drug susceptible, 11 were resistant only to nitrofurans, and 3 were streptomycin, spectinomycin, and nitrofuran resistant ; none of these 21 isolates harbored plasmid DNA.

    Most isolates (n=107) were resistant to nitrofurans (chromosomal) and to streptomycin, spectinomycin, sulfonamides, tetracycline, and mercuric and tellurite salts ; this multidrug resistance was encoded on a 218-kb plasmid classified in a number of strains as being in the IncHl2 group.

    From 1982 to 1993,11 isolates acquired an additional self-transferable plasmid coding for resistance to any one of ampicillin (61 kb), ampicillin and trimethoprim (65 kb), ampicillin, trimethoprim, streptomycin, and sulfonamides (71 kb), ampicillin, gentamicin, kanamycin, and tetracycline (120 kb), or a nontransferable plasmid of ~6 kb encoding resistance to ampicillin or kanamycin.

    With the exception of ampicillin or ampicillin and trimethoprim resistance, S. panama isolates from foodstuffs, mainly pork meat products, and animals had resistance patterns that were th...

    Mots-clés Pascal : Salmonella panama, Enterobacteriaceae, Bactérie, Antibiotique, Antibactérien, Résistance, Chili, Amérique du Sud, Amérique, Epidémiologie, Dissémination

    Mots-clés Pascal anglais : Salmonella panama, Enterobacteriaceae, Bacteria, Antibiotic, Antibacterial agent, Resistance, Chile, South America, America, Epidemiology, Dissemination

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0122367

    Code Inist : 002A05B11. Création : 199608.