Our objective was to identify the determinants of plasma levels of anti-oxidant vitamins which have been linked with decreased risk of cancer and other chronic diseases.
Correlation analyses were performed between baseline plasma levels of ascorbic acid, alpha-and bêta-carotenes, cryptoxanthin, lycopene and alpha-and gamma-tocopherols and baseline information on dietary and other demographic and life-style factors among 1,364 subjects 35-69 years of age, who are participants in a chemoprevention trial on pre-cancerous lesions of the stomach in Venezuela.
Males had lower levels of ascorbic acid, alpha-and bêta-carotene and cryptoxanthin and higher levels of alpha-tocopherol than females.
This finding was confirmed in non-smokers and non-drinkers.
In females, but not in males, age was positively associated with levels of ascorbic acid, cryptoxanthin, alpha-and bêta-carotene and gamma-tocopherol.
Male tobacco users had lower plasma levels of ascorbic acid, alpha-and bêta-carotene and cryptoxanthin than non-users, and regular alcohol drinkers had a decreased plasma levels of bêta-carotene compared with non-drinkers.
Female tobacco users had lower levels of ascorbic acid and cryptoxanthin than non-users, and regular alcohol drinkers had lower levels of ascorbic acid and lycopene than non-drinkers.
Frequencies of consumption of fresh fruits, fruit juice, raw vegetables and plantains showed weak positive associations with plasma levels of several vitamins studied...
Mots-clés Pascal : Tumeur maligne, Estomac, Facteur risque, Epidémiologie, Antioxydant, Vitamine, Plasma sanguin, Venezuela, Amérique du Sud, Amérique, Fruit, Jus fruit, Légume, Tabagisme, Alcoolisme, Homme, Appareil digestif pathologie, Estomac pathologie
Mots-clés Pascal anglais : Malignant tumor, Stomach, Risk factor, Epidemiology, Antioxidant, Vitamin, Blood plasma, Venezuela, South America, America, Fruit, Fruit juice, Vegetable, Tobacco smoking, Alcoholism, Human, Digestive diseases, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0121369
Code Inist : 002B13B01. Création : 199608.