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  1. Determinants of plasma anti-oxidant vitamin levels in a population at high risk for stomach cancer.

    Article - En anglais

    Our objective was to identify the determinants of plasma levels of anti-oxidant vitamins which have been linked with decreased risk of cancer and other chronic diseases.

    Correlation analyses were performed between baseline plasma levels of ascorbic acid, alpha-and bêta-carotenes, cryptoxanthin, lycopene and alpha-and gamma-tocopherols and baseline information on dietary and other demographic and life-style factors among 1,364 subjects 35-69 years of age, who are participants in a chemoprevention trial on pre-cancerous lesions of the stomach in Venezuela.

    Males had lower levels of ascorbic acid, alpha-and bêta-carotene and cryptoxanthin and higher levels of alpha-tocopherol than females.

    This finding was confirmed in non-smokers and non-drinkers.

    In females, but not in males, age was positively associated with levels of ascorbic acid, cryptoxanthin, alpha-and bêta-carotene and gamma-tocopherol.

    Male tobacco users had lower plasma levels of ascorbic acid, alpha-and bêta-carotene and cryptoxanthin than non-users, and regular alcohol drinkers had a decreased plasma levels of bêta-carotene compared with non-drinkers.

    Female tobacco users had lower levels of ascorbic acid and cryptoxanthin than non-users, and regular alcohol drinkers had lower levels of ascorbic acid and lycopene than non-drinkers.

    Frequencies of consumption of fresh fruits, fruit juice, raw vegetables and plantains showed weak positive associations with plasma levels of several vitamins studied...

    Mots-clés Pascal : Tumeur maligne, Estomac, Facteur risque, Epidémiologie, Antioxydant, Vitamine, Plasma sanguin, Venezuela, Amérique du Sud, Amérique, Fruit, Jus fruit, Légume, Tabagisme, Alcoolisme, Homme, Appareil digestif pathologie, Estomac pathologie

    Mots-clés Pascal anglais : Malignant tumor, Stomach, Risk factor, Epidemiology, Antioxidant, Vitamin, Blood plasma, Venezuela, South America, America, Fruit, Fruit juice, Vegetable, Tobacco smoking, Alcoholism, Human, Digestive diseases, Gastric disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0121369

    Code Inist : 002B13B01. Création : 199608.