A prospective 1-5 year outcome study in first-admitted and readmitted schizophrenic patients ; relationship to heredity, premorbid adjustment, duration of disease and education level at index admission and neuroleptic treatment.
In a prospective outcome study, 120 DSM-III-R schizophrenic patients were followed for up to 5 years after index admission, when a comprehensive clinical and demographical examination was undertaken with the aim to find early prognostic factors for outcome.
They were 86 males (72%) and 34 females (28%), and 66 (55%) were first-admitted and never before treated at index admission from a geographically defined area.
Outcome was evaluated 1,3 and 5 years after index admission by use of a Strauss-Carpenter outcome scale.
At year five, 101 patients could be evaluated.
Seven (7%) patients had committed suicide during the 5 years'follow-up period. 30% of the patients was considered to have a good, 14% a poor and 56% an intermediate outcome.
It was found that 58% had not been in hospital during the last year, 27% were employed on the open market, 25% met friends regularly and 38% had no or only mild symptoms at the five years'follow-up evaluation.
Females had a significantly better outcome than males.
High education level and absence of premorbid deviant behaviour at index admission predicted a good outcome whereas problems in school (with friends and/or teachers) reported by relatives predicted poor outcome.
No relationship was found between outcome and age at onset of the disorder and no gender difference in age at onset of the disorder.
Patients with a family history of schizophrenia improved more between year one and five as compared with those without a famil...
Mots-clés Pascal : Schizophrénie, Psychose, Etude longitudinale, Evolution, Pronostic, Etude familiale, Déterminisme génétique, Antécédent, Durée, Niveau étude, Démographie, Homme, Enquête, Epidémiologie
Mots-clés Pascal anglais : Schizophrenia, Psychosis, Follow up study, Evolution, Prognosis, Family study, Genetic inheritance, Antecedent, Duration, Education level, Demography, Human, Inquiry, Epidemiology
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0112796
Code Inist : 002B18C06A. Création : 199608.