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  1. Effect of comprehensive intervention program on survival of patients with human immunodeficiency virus infection.

    Article - En anglais


    In October 1989, an early intervention program (EIP) for human immunodeficiency virus (HIV) infection was initiated in New Jersey to provide medical care and social services to the enrollees.


    To assess the overall effect of the EIP on the survival of HIV-infected patients.


    Patient information collected through June 30,1993, was analyzed from the Jersey City Medical Center EIP clinic.

    Survival from enrollment to death was calculated for patients who received follow-up at the clinic (active) and for those who only had the enrollment visit (inactive).

    The data were matched with the New Jersey death certificate registry.


    Of 938 patients enrolled from October 1989 to December 1991,767 had T-cell subsets determined within 3 months of enrollment : 641 patients were active and 126 were inactive.

    At entry, inactive patients had a lower median CD4+T-cell count and were more likely to be symptomatic than active patients.

    Among the 640 active and 125 inactive patients analyzed for survival (survivors = 2 months), there were 144 (22.5%) and 48 (38.4%) deaths, respectively.

    Kaplan-Meier analysis indicated longer survival for active patients than for inactive patients (P<. 001, Wilcoxon's test for homogeneity of strata) ; eg, survival probability at 2 years was 86% for active patients and 64% for inactive patients.

    Active patients also had longer survival than inactive patients when stratified by CD4+T-cell levels or by clinic...

    Mots-clés Pascal : SIDA, Virose, Infection, Information biomédicale, Malade, Corrélation, Survie, Epidémiologie, Homme, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Biomedical information, Patient, Correlation, Survival, Epidemiology, Human, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0109739

    Code Inist : 002B06D01. Création : 199608.