- To determine the relative frequencies of primary and reactivation tuberculosis in the urban homeless.
- Prospective evaluation of homeless tuberculosis patients.
- Central Los Angeles, Calif.
- Thirty-four homeless patients with culture-proven tuberculosis.
- IS6110-based restriction fragment length polymorphism (RFLP) analysis was performed on Mycobacterium tuberculosis isolates.
If results were inconclusive, pTBN12-based RFLP analysis was performed.
- Clustering of M tuberculosis isolates.
A cluster consisted of two or more isolates with indistinguishable RFLP patterns.
- Twenty-four of 34 homeless patients had clustered isolates in six clusters.
- The minimum percentage of cases due to primary tuberculosis in the homeless was estimated to be 53%, compared with the traditional estimate of 10% in the general population.
The results suggest that primary tuberculosis caused the majority of tuberculosis cases in this population of the urban homeless in central Los Angeles.
Mots-clés Pascal : Tuberculose, Mycobactériose, Bactériose, Infection, Poumon, Primoinfection, Transmission homme homme, Sans domicile fixe, Réactivation, Californie, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Homme, Appareil respiratoire pathologie, Poumon pathologie
Mots-clés Pascal anglais : Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Lung, Primary infection, Transmission from man to man, Homeless, Reactivation, California, United States, North America, America, Epidemiology, Human, Respiratory disease, Lung disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0106878
Code Inist : 002B05B02O. Création : 199608.