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  1. Transmission of tuberculosis among the urban homeless.

    Article - En anglais

    Objective

    - To determine the relative frequencies of primary and reactivation tuberculosis in the urban homeless.

    Design

    - Prospective evaluation of homeless tuberculosis patients.

    Setting

    - Central Los Angeles, Calif.

    Patients

    - Thirty-four homeless patients with culture-proven tuberculosis.

    Interventions

    - IS6110-based restriction fragment length polymorphism (RFLP) analysis was performed on Mycobacterium tuberculosis isolates.

    If results were inconclusive, pTBN12-based RFLP analysis was performed.

    Main Outcome Measure

    - Clustering of M tuberculosis isolates.

    A cluster consisted of two or more isolates with indistinguishable RFLP patterns.

    Results

    - Twenty-four of 34 homeless patients had clustered isolates in six clusters.

    Conclusions

    - The minimum percentage of cases due to primary tuberculosis in the homeless was estimated to be 53%, compared with the traditional estimate of 10% in the general population.

    The results suggest that primary tuberculosis caused the majority of tuberculosis cases in this population of the urban homeless in central Los Angeles.

    Mots-clés Pascal : Tuberculose, Mycobactériose, Bactériose, Infection, Poumon, Primoinfection, Transmission homme homme, Sans domicile fixe, Réactivation, Californie, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Homme, Appareil respiratoire pathologie, Poumon pathologie

    Mots-clés Pascal anglais : Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Lung, Primary infection, Transmission from man to man, Homeless, Reactivation, California, United States, North America, America, Epidemiology, Human, Respiratory disease, Lung disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0106878

    Code Inist : 002B05B02O. Création : 199608.