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  1. A cluster of cases of streptococcal necrotizing fasciitis in Gloucestershire.

    Article - En anglais

    We describe the first cluster of cases of necrotizing fasciitis (NF) in this century in the United Kingdom (UK).

    Between 1 January and 30 June 1994 there were six cases (five confirmed, one probable) of Streptococcus pyogenes NF in west Gloucestershire, population 320000.

    Two cases died.

    The first two patients probably acquired their infections during the course of elective surgery performed in the same operating theatre, possibly from a nasopharyngeal carrier amongst the theatre staff.

    The remaining infections were community-acquired.

    Of 5 S. pyogenes isolates there were 2 M1 strains, 1 M3,1 M5 and 1 M non-typeable strain.

    S. pyogenes NF had not been recorded in west Gloucestershire in the preceding 10 years and the incidence of S. pyoqenes bacteraemia in England and Wales had not risen in the past 5 years.

    The two presumably theatre-acquired infections raised several issues.

    The need for detailed bacteriological investigation of all cases of post-surgical NF was confirmed.

    Clusters of S. pyogenes infection following surgery should be managed by closure of the operating theatre until all staff have been screened for carriage.

    Closure of an operating theatre and screening of staff following a sporadic case is probably not justified because of the infrequency of surgical cross-infection with S. pyogenes.

    Regular, routine screening of theatre staff is neither practical nor necessary.

    Mots-clés Pascal : Etude cas, Homme, Streptococcus pyogenes, Streptococcaceae, Micrococcales, Bactérie, Streptococcie, Bactériose, Infection, Epidémiologie, Pullulation, Fasciite nécrosante, Peau pathologie, Tissu conjonctif pathologie

    Mots-clés Pascal anglais : Case study, Human, Streptococcus pyogenes, Streptococcaceae, Micrococcales, Bacteria, Streptococcal infection, Bacteriosis, Infection, Epidemiology, Outbreak, Necrotizing fasciitis, Skin disease, Connective tissue disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0103935

    Code Inist : 002B05B02N. Création : 199608.