Diagnostic x rays are the largest man-made source of exposure to ionizing radiation for the general population.
Whether there are meaningful cancer risks associated with such exposures is unclear.
Most previous case-control studies have relied on recalled histories of x rays, and there is concern that completeness and accuracy of recall might differ between cancer case and control subjects.
The present study used information recorded prospectively in hospital charts to address the relationship between medical diagnostic x rays and risk of thyroid cancer.
The Swedish Cancer Registry and the Uppsala-Orebro Regional Cancer Registry were used to identify persons with papillary or follicular thyroid cancer diagnosed from January 1,1980, through December 31,1992, among residents of the Uppsala Health Care Region.
After histopathologic review, there were 484 such case subjects available for study.
An equal number of age-sex-and county of residence-matched control subjects from the general population were randomly selected on the basis of the Swedish Registry of the Total Population.
Lifetime residential histories were compiled, and radiology records were searched at all Swedish hospitals serving regions where study subjects ever maintained an official residence.
Approximate radiation doses to the thyroid gland for specific types of x-ray examinations were assigned on the basis of mean values of measurements made in Sweden in 1973-...
Mots-clés Pascal : Tumeur maligne, Thyroïde, Facteur risque, Epidémiologie, Rayonnement ionisant, Rayon X, Radiodiagnostic, Suède, Europe, Homme, Endocrinopathie, Thyroïde pathologie, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Thyroid gland, Risk factor, Epidemiology, Ionizing radiation, X ray, Radiodiagnosis, Sweden, Europe, Human, Endocrinopathy, Thyroid diseases, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0091058
Code Inist : 002B21C02. Création : 199608.