Mammographic features and breast cancer risk : effects with time, age, and menopause status.
Mammographic images from women with a high proportion of epithelial and stromal breast tissues are described as showing high-density parenchymal patterns.
Most past studies that noted an increase in breast cancer risk associated with mammographic parenchymal patterns showing high density either 1) lacked information on other breast cancer risk factors, 2) were too small, or 3) included insufficient follow-up time to adequately resolve persisting doubts whether mammographic features are « independent » measures of breast cancer risk and not a detection artifact.
The purpose of this study was twofold : 1) to evaluate the associations between mammographic features and other breast cancer risk factors and 2) to assess effects of mammographic features on breast cancer risk by time, age, and menopause status.
To address these questions, we analyzed detailed information from a large, nested case-control study with 16 years of follow-up.
This study used information from both screening and follow-up phases of the Breast Cancer Detection Demonstration Project, a nationwide program that offered annual breast cancer screening for more than 280 000 women from 1973 to 1980.
Mammographic features were assessed from the base-line screening mammographic examination for 1880 incident case subjects and 2152 control subjects.
Control subjects were randomly selected from women of the same age and race as each case subject.
Control subjects attend...
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Densité, Parenchyme, Epidémiologie, Mammographie, Exploration radiologique, Temps, Age, Ménopause, Etats Unis, Amérique du Nord, Amérique, Homme, Glande mammaire pathologie, Radiodiagnostic
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Density, Parenchyma, Epidemiology, Mammography, Radiologic investigation, Time, Age, Menopause, United States, North America, America, Human, Mammary gland diseases, Radiodiagnosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0090417
Code Inist : 002B20E02. Création : 199608.