Objectives-A hospital based case-control study was conducted between 1992 and 1993 in the province of Brescia, a highly industrialised area in northern Italy, to evaluate occupational risk factors of bladder cancer.
Method-The study evaluated 355 histologically confirmed cases of bladder cancer (275 men, 80 women) and 579 controls affected by urological non-neoplastic diseases (397 men, 182 women).
Lifetime occupational history, smoking and drinking habits, and sociodemographic characteristics were recorded by means of a structured questionnaire.
Odds ratios (ORs) were computed with adjustment for age, smoking, alcohol and coffee consumption, education, and place of residence.
A significant (P<0.05) increase of risk of bladder cancer was found in men for labourers in the construction industry (OR 2.1,95% confidence interval (95% CI) 1.1-3.9) and for recreational and cultural services (OR 5.0,95% CI 1.3-18.9).
Increased risks, although not significant, were found for various other occupations and industries such as machinery mechanics, metal processers and polishers, blacksmiths, gunsmiths, painters ; for transport workers, an increased risk with increasing duration of employment was found.
Conclusions-Occupational exposures seem to contribute to bladder cancer risk in the area under study.
Mots-clés Pascal : Tumeur maligne, Vessie urinaire, Homme, Appareil urinaire pathologie, Exposition professionnelle, Médecine travail, Epidémiologie, Italie, Europe, Zone industrielle
Mots-clés Pascal anglais : Malignant tumor, Urinary bladder, Human, Urinary system disease, Occupational exposure, Occupational medicine, Epidemiology, Italy, Europe, Industrial area
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0084365
Code Inist : 002B14D02. Création : 199608.