Chickens were used as a model for foraging animals to examine the bioavailability of all 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/PCDFs) from soil.
Three groups of chickens were exposed through their diet to soil contaminated with PCDD/PCDFs at less than 0.5 pg/g I-TEQ (control group), 42 pg/g I-TEQ (low exposure group), and 460 pg/g I-TEQs (high exposure group).
Eggs, tissues, feces and feed were analysed throughout the exposure and depuration period.
Daily intake was estimated at 2.5 ng/kg-day for the high and 0.3 ng/kg-day for the low exposure groups.
Bioavailability was chlorination-dependent ranging from 80% for tetrachlorinated to less than 10% for octachlorinated congeners.
During exposure, tissue distribution was congener-dependent with 5-30% of the intake excreted in the eggs, 7-54% deposited in the adipose and less than 1% present in the liver.
On a fat weight basis, the highest concentrations were observed in the liver, implying that mechanisms other than lipid solubility operate in that tissue.
Bioconcentration factors and elimination half-lives were also congener-and tissue-dependent.
Results from this study indicate that animals foraging on soil contaminated at low ppt PCDD/PCDF levels may bioaccumulate these compounds to unacceptable levels.
Mots-clés Pascal : Dibenzo-p-dioxine(2,3,7,8-tétrachloro), Dibenzofurane(polychloro), Dibenzo-p-dioxine(polychloro), Poulet, Aves, Vertebrata, Animal, Polluant, Sol, Accumulation biologique, Biodisponibilité, Métabolisme, Distribution, Comportement alimentaire, Animal élevage, Contamination, Homme, Viande, Aliment, Toxicité
Mots-clés Pascal anglais : Chicken, Aves, Vertebrata, Animal, Pollutant, Soils, Biological accumulation, Bioavailability, Metabolism, Distribution, Feeding behavior, Farming animal, Contamination, Human, Meat, Food, Toxicity
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0081087
Code Inist : 002A14D05H3. Création : 199608.